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Weighted Correlation Network Analysis Reveals CDK2 as a Regulator of a Ubiquitous Environmental Toxin-Induced Cell-Cycle Arrest

Environmental food contaminants constitute a threat to human health. For instance, the globally spread mycotoxin Ochratoxin A (OTA) contributes to chronic kidney damage by affecting proximal tubule cells via unknown mechanisms. We applied a top-down approach to identify relevant toxicological mechan...

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Detalles Bibliográficos
Autores principales: Dubourg, Virginie, Nolze, Alexander, Kopf, Michael, Gekle, Michael, Schwerdt, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017252/
https://www.ncbi.nlm.nih.gov/pubmed/31936152
http://dx.doi.org/10.3390/cells9010143