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Weighted Correlation Network Analysis Reveals CDK2 as a Regulator of a Ubiquitous Environmental Toxin-Induced Cell-Cycle Arrest
Environmental food contaminants constitute a threat to human health. For instance, the globally spread mycotoxin Ochratoxin A (OTA) contributes to chronic kidney damage by affecting proximal tubule cells via unknown mechanisms. We applied a top-down approach to identify relevant toxicological mechan...
Autores principales: | Dubourg, Virginie, Nolze, Alexander, Kopf, Michael, Gekle, Michael, Schwerdt, Gerald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017252/ https://www.ncbi.nlm.nih.gov/pubmed/31936152 http://dx.doi.org/10.3390/cells9010143 |
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