Cargando…

Chaperoning STAT3/5 by Heat Shock Proteins: Interest of Their Targeting in Cancer Therapy

While cells from multicellular organisms are dependent upon exogenous signals for their survival, growth, and proliferation, commitment to a specific cell fate requires the correct folding and maturation of proteins, as well as the degradation of misfolded or aggregated proteins within the cell. Thi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jego, Gaëtan, Hermetet, François, Girodon, François, Garrido, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017265/ https://www.ncbi.nlm.nih.gov/pubmed/31861612 http://dx.doi.org/10.3390/cancers12010021

Ejemplares similares

Heat Shock Proteins and PD-1/PD-L1 as Potential Therapeutic Targets in Myeloproliferative Neoplasms
por: De Almeida, Steven, et al.
Publicado: (2020)

Heat-Shock Proteins in Leukemia and Lymphoma: Multitargets for Innovative Therapeutic Approaches
por: Cabaud-Gibouin, Vincent, et al.
Publicado: (2023)

Genetic Background of Polycythemia Vera
por: Regimbeau, Mathilde, et al.
Publicado: (2022)

The heat‐shock protein/chaperone network and multiple stress resistance
por: Jacob, Pierre, et al.
Publicado: (2017)

Investigation of the chaperone function of the small heat shock protein — AgsA
por: Tomoyasu, Toshifumi, et al.
Publicado: (2010)

Heat Shock Proteins: A Review of the Molecular Chaperones for Plant Immunity
por: Park, Chang-Jin, et al.
Publicado: (2015)

DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network
por: Hammond, Colin M., et al.
Publicado: (2021)

Expression of one important chaperone protein, heat shock protein 27, in neurodegenerative diseases
por: Zhang, Xuekai, et al.
Publicado: (2014)

Regulation of SKP2 protein stability by heat shock protein 90 chaperone machinery
por: Cai, Lili, et al.
Publicado: (2021)

A Novel Mechanism for Small Heat Shock Proteins to Function as Molecular Chaperones
por: Zhang, Kaiming, et al.
Publicado: (2015)

Screening Molecular Chaperones Similar to Small Heat Shock Proteins in Schizosaccharomyces pombe
por: Han, Jiyoung, et al.
Publicado: (2015)

Using bicistronic constructs to evaluate the chaperone activities of heat shock proteins in cells
por: San Gil, Rebecca, et al.
Publicado: (2017)

Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space
por: Adriaenssens, Elias, et al.
Publicado: (2023)

HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis
por: Sevin, Margaux, et al.
Publicado: (2018)

Heat Shock Protein 90 Chaperones E1A Early Protein of Adenovirus 5 and Is Essential for Replication of the Virus
por: Dalidowska, Iga, et al.
Publicado: (2021)

Heat shock-induced chaperoning by Hsp70 is enabled in-cell
por: Guin, Drishti, et al.
Publicado: (2019)

Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA
Publicado: (1994)

Heat Shock Proteins and Amateur Chaperones in Amyloid-Beta Accumulation and Clearance in Alzheimer’s Disease
por: Wilhelmus, Micha M. M., et al.
Publicado: (2007)

Small Molecule Inhibitors to Disrupt Protein-protein Interactions of Heat Shock Protein 90 Chaperone Machinery
por: Seo, Young Ho
Publicado: (2015)

Heat Shock Proteins: Cell Protection through Protein Triage
por: Lanneau, David, et al.
Publicado: (2010)

Synergistic promotion of breast cancer cells death by targeting molecular chaperone GRP78 and heat shock protein 70
por: Li, Minjing, et al.
Publicado: (2009)

Chaperone-Based Therapeutic Target Innovation: Heat Shock Protein 70 (HSP70) for Type 2 Diabetes Mellitus
por: Mulyani, W. Riski Widya, et al.
Publicado: (2020)

Heat Shock Protein 90 Chaperone Regulates the E3 Ubiquitin-Ligase Hakai Protein Stability
por: Díaz-Díaz, Andrea, et al.
Publicado: (2020)

Antimyeloma Effects of the Heat Shock Protein 70 Molecular Chaperone Inhibitor MAL3-101
por: Braunstein, Marc J., et al.
Publicado: (2011)

Functional Characterization of an Arabidopsis Profilin Protein as a Molecular Chaperone under Heat Shock Stress
por: Son, Hyosuk, et al.
Publicado: (2022)

Extracellular Heat Shock Proteins as Therapeutic Targets and Biomarkers in Fibrosing Interstitial Lung Diseases
por: Tanguy, Julie, et al.
Publicado: (2021)

P1267: HSP110 FAVORS BCR SIGNALING THROUGH SYK PHOSPHORYLATION IN DIFFUSE LARGE B CELL LYMPHOMA
por: Cabaud Gibouin, V., et al.
Publicado: (2022)

P1217: TARGETING HSP110 IN COMBINATION WITH SELINEXOR IN PRIMARY MEDIASTINAL B-CELL LYMPHOMA AND IN CLASSICAL HODGKIN LYMPHOMA INHIBITS STAT6 ACTIVATION AND IMPAIRS LYMPHOMA CELL GROWTH
por: Durand, Manon, et al.
Publicado: (2023)

HSP90 and HSP70: Implication in Inflammation Processes and Therapeutic Approaches for Myeloproliferative Neoplasms
por: Sevin, Margaux, et al.
Publicado: (2015)

Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis
por: Thuringer, Dominique, et al.
Publicado: (2016)

Heat Shock Proteins as Danger Signals for Cancer Detection
por: Seigneuric, Renaud, et al.
Publicado: (2011)

Chaperoning to the metabolic party: The emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetes
por: Henstridge, Darren C., et al.
Publicado: (2014)

O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity
por: Balana, Aaron T., et al.
Publicado: (2021)

Molecular chaperone function of three small heat-shock proteins from a model probiotic species
por: Rocchetti, Maria Teresa, et al.
Publicado: (2022)

Site-Specific Glycation of Human Heat Shock Protein (Hsp27) Enhances Its Chaperone Activity
por: Mukherjee, Somnath, et al.
Publicado: (2023)

Pharmacological heat-shock protein inducers and chemical chaperones inhibit upregulation of interleukin-8 by oxidized phospholipids
por: Hellauer, Klara, et al.
Publicado: (2023)

A Review on the Involvement of Heat Shock Proteins (Extrinsic Chaperones) in Response to Stress Conditions in Aquatic Organisms
por: Jeyachandran, Sivakamavalli, et al.
Publicado: (2023)

Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells
por: Tanaka, Tsutomu, et al.
Publicado: (2015)

Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation
por: Perotti, Christian, et al.
Publicado: (2008)

Targeting Heat-Shock Protein 90 in Cancer: An Update on Combination Therapy
por: Ren, Xiude, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u4d3grjcg3te4sf8qpftk7fmun