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HB-EGF–EGFR Signaling in Bone Marrow Endothelial Cells Mediates Angiogenesis Associated with Multiple Myeloma

Epidermal growth factor receptor (EGFR) and its ligand heparin-binding EGF-like growth factor (HB-EGF) sustain endothelial cell proliferation and angiogenesis in solid tumors, but little is known about the role of HB-EGF–EGFR signaling in bone marrow angiogenesis and multiple myeloma (MM) progressio...

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Detalles Bibliográficos
Autores principales: Rao, Luigia, Giannico, Donato, Leone, Patrizia, Solimando, Antonio Giovanni, Maiorano, Eugenio, Caporusso, Concetta, Duda, Loren, Tamma, Roberto, Mallamaci, Rosanna, Susca, Nicola, Buonavoglia, Alessio, Da Vià, Matteo Claudio, Ribatti, Domenico, De Re, Vallì, Vacca, Angelo, Racanelli, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017291/
https://www.ncbi.nlm.nih.gov/pubmed/31936715
http://dx.doi.org/10.3390/cancers12010173