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HB-EGF–EGFR Signaling in Bone Marrow Endothelial Cells Mediates Angiogenesis Associated with Multiple Myeloma
Epidermal growth factor receptor (EGFR) and its ligand heparin-binding EGF-like growth factor (HB-EGF) sustain endothelial cell proliferation and angiogenesis in solid tumors, but little is known about the role of HB-EGF–EGFR signaling in bone marrow angiogenesis and multiple myeloma (MM) progressio...
Autores principales: | Rao, Luigia, Giannico, Donato, Leone, Patrizia, Solimando, Antonio Giovanni, Maiorano, Eugenio, Caporusso, Concetta, Duda, Loren, Tamma, Roberto, Mallamaci, Rosanna, Susca, Nicola, Buonavoglia, Alessio, Da Vià, Matteo Claudio, Ribatti, Domenico, De Re, Vallì, Vacca, Angelo, Racanelli, Vito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017291/ https://www.ncbi.nlm.nih.gov/pubmed/31936715 http://dx.doi.org/10.3390/cancers12010173 |
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