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SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells
B3GALT5 is involved in the synthesis of embryonic stem (ES) cell marker glycan, stage-specific embryonic antigen-3 (SSEA3). This gene has three native promoters and an integrated retroviral long terminal repeat (LTR) promoter. We found that B3GALT5-LTR is expressed at high levels in human ES cells....
Autores principales: | Cai, Bi-He, Lee, Hsueh-Yi, Chou, Chi-Kan, Wu, Po-Han, Huang, Hsiang-Chi, Chao, Chia-Chun, Chung, Hsiao-Yu, Kannagi, Reiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017369/ https://www.ncbi.nlm.nih.gov/pubmed/31936807 http://dx.doi.org/10.3390/cells9010177 |
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