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Targeted Nano-Drug Delivery of Colchicine against Colon Cancer Cells by Means of Mesoporous Silica Nanoparticles
Antimitotics are important anticancer agents and include the natural alkaloid prodrug colchicine (COL). However, a major challenge of using COL as an anticancer drug is its cytotoxicity. We developed a novel drug delivery system (DDS) for COL using mesoporous silica nanoparticles (MSNs). The MSNs we...
Autores principales: | AbouAitah, Khaled, Hassan, Heba A., Swiderska-Sroda, Anna, Gohar, Lamiaa, Shaker, Olfat G., Wojnarowicz, Jacek, Opalinska, Agnieszka, Smalc-Koziorowska, Julita, Gierlotka, Stanislaw, Lojkowski, Witold |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017376/ https://www.ncbi.nlm.nih.gov/pubmed/31936103 http://dx.doi.org/10.3390/cancers12010144 |
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