Digital imaging-assisted quantification of H3K27me3 immunoexpression in luminal A/B-like, HER2-negative, invasive breast cancer predicts patient survival and risk of recurrence

BACKGROUND: Breast cancer (BC) is a major health concern and better understanding of its biology might improve treatment decisions and patient outcomes. Histone3 Lysine27 tri-methylation (H3K27me3) is a post-translational histone modification frequently associated with altered gene expression. In BC...

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Detalles Bibliográficos
Autores principales: Fontes-Sousa, Mário, Lobo, João, Lobo, Silvana, Salta, Sofia, Amorim, Maria, Lopes, Paula, Antunes, Luís, de Sousa, Susana Palma, Henrique, Rui, Jerónimo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017542/
https://www.ncbi.nlm.nih.gov/pubmed/32050892
http://dx.doi.org/10.1186/s10020-020-0147-5

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