Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data

BACKGROUND: Many functional analysis tools have been developed to extract functional and mechanistic insight from bulk transcriptome data. With the advent of single-cell RNA sequencing (scRNA-seq), it is in principle possible to do such an analysis for single cells. However, scRNA-seq data has chara...

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Detalles Bibliográficos
Autores principales: Holland, Christian H., Tanevski, Jovan, Perales-Patón, Javier, Gleixner, Jan, Kumar, Manu P., Mereu, Elisabetta, Joughin, Brian A., Stegle, Oliver, Lauffenburger, Douglas A., Heyn, Holger, Szalai, Bence, Saez-Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017576/
https://www.ncbi.nlm.nih.gov/pubmed/32051003
http://dx.doi.org/10.1186/s13059-020-1949-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017576/
https://www.ncbi.nlm.nih.gov/pubmed/32051003
http://dx.doi.org/10.1186/s13059-020-1949-z

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