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Supramolecular caging for cytosolic delivery of anionic probes
The cytosolic delivery of hydrophilic, anionic molecular probes and therapeutics is a major challenge in chemical biology and medicine. Herein, we describe the design and synthesis of peptide–cage hybrids that allow an efficient supramolecular binding, cell membrane translocation and cytosolic deliv...
Autores principales: | Fernández-Caro, Héctor, Lostalé-Seijo, Irene, Martínez-Calvo, Miguel, Mosquera, Jesús, Mascareñas, José L., Montenegro, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017865/ https://www.ncbi.nlm.nih.gov/pubmed/32110291 http://dx.doi.org/10.1039/c9sc02906k |
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