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Supramolecular caging for cytosolic delivery of anionic probes

The cytosolic delivery of hydrophilic, anionic molecular probes and therapeutics is a major challenge in chemical biology and medicine. Herein, we describe the design and synthesis of peptide–cage hybrids that allow an efficient supramolecular binding, cell membrane translocation and cytosolic deliv...

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Detalles Bibliográficos
Autores principales: Fernández-Caro, Héctor, Lostalé-Seijo, Irene, Martínez-Calvo, Miguel, Mosquera, Jesús, Mascareñas, José L., Montenegro, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017865/
https://www.ncbi.nlm.nih.gov/pubmed/32110291
http://dx.doi.org/10.1039/c9sc02906k

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