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A transition-metal-free & diazo-free styrene cyclopropanation
An operationally simple and broadly applicable novel cyclopropanation of styrenes using gem-diiodomethyl carbonyl reagents has been developed. Visible-light triggered the photoinduced generation of iodomethyl carbonyl radicals, able to cyclopropanate a wide array of styrenes with excellent chemosele...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017872/ https://www.ncbi.nlm.nih.gov/pubmed/32110302 http://dx.doi.org/10.1039/c9sc02749a |
| _version_ | 1783497266535858176 |
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| author | Herraiz, Ana G. Suero, Marcos G. |
| author_facet | Herraiz, Ana G. Suero, Marcos G. |
| author_sort | Herraiz, Ana G. |
| collection | PubMed |
| description | An operationally simple and broadly applicable novel cyclopropanation of styrenes using gem-diiodomethyl carbonyl reagents has been developed. Visible-light triggered the photoinduced generation of iodomethyl carbonyl radicals, able to cyclopropanate a wide array of styrenes with excellent chemoselectivity and functional group tolerance. To highlight the utility of our photocyclopropanation, we demonstrated the late-stage functionalization of biomolecule derivatives. |
| format | Online Article Text |
| id | pubmed-7017872 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | Royal Society of Chemistry |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-70178722020-02-27 A transition-metal-free & diazo-free styrene cyclopropanation Herraiz, Ana G. Suero, Marcos G. Chem Sci Chemistry An operationally simple and broadly applicable novel cyclopropanation of styrenes using gem-diiodomethyl carbonyl reagents has been developed. Visible-light triggered the photoinduced generation of iodomethyl carbonyl radicals, able to cyclopropanate a wide array of styrenes with excellent chemoselectivity and functional group tolerance. To highlight the utility of our photocyclopropanation, we demonstrated the late-stage functionalization of biomolecule derivatives. Royal Society of Chemistry 2019-08-28 /pmc/articles/PMC7017872/ /pubmed/32110302 http://dx.doi.org/10.1039/c9sc02749a Text en This journal is © The Royal Society of Chemistry 2019 http://creativecommons.org/licenses/by-nc/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported Licence (CC BY-NC 3.0) |
| spellingShingle | Chemistry Herraiz, Ana G. Suero, Marcos G. A transition-metal-free & diazo-free styrene cyclopropanation |
| title | A transition-metal-free & diazo-free styrene cyclopropanation
|
| title_full | A transition-metal-free & diazo-free styrene cyclopropanation
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| title_fullStr | A transition-metal-free & diazo-free styrene cyclopropanation
|
| title_full_unstemmed | A transition-metal-free & diazo-free styrene cyclopropanation
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| title_short | A transition-metal-free & diazo-free styrene cyclopropanation
|
| title_sort | transition-metal-free & diazo-free styrene cyclopropanation |
| topic | Chemistry |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017872/ https://www.ncbi.nlm.nih.gov/pubmed/32110302 http://dx.doi.org/10.1039/c9sc02749a |
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