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In vivo glucoregulation and tissue-specific glucose uptake in female Akt substrate 160 kDa knockout rats

The Rab GTPase activating protein known as Akt substrate of 160 kDa (AS160 or TBC1D4) regulates insulin-stimulated glucose uptake in skeletal muscle, the heart, and white adipose tissue (WAT). A novel rat AS160-knockout (AS160-KO) was created with CRISPR/Cas9 technology. Because female AS160-KO vers...

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Detalles Bibliográficos
Autores principales:	Zheng, Xiaohua, Arias, Edward B., Qi, Nathan R., Saunders, Thomas L., Cartee, Gregory D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018090/ https://www.ncbi.nlm.nih.gov/pubmed/32053588 http://dx.doi.org/10.1371/journal.pone.0223340

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