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Interaction of yeast Rad51 and Rad52 relieves Rad52-mediated inhibition of de novo telomere addition
DNA double-strand breaks (DSBs) are toxic forms of DNA damage that must be repaired to maintain genome integrity. Telomerase can act upon a DSB to create a de novo telomere, a process that interferes with normal repair and creates terminal deletions. We previously identified sequences in Saccharomyc...
Autores principales: | Epum, Esther A., Mohan, Michael J., Ruppe, Nicholas P., Friedman, Katherine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018233/ https://www.ncbi.nlm.nih.gov/pubmed/32012161 http://dx.doi.org/10.1371/journal.pgen.1008608 |
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