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Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial
BACKGROUND/AIM: Body weight-supported treadmill training (BWSTT) might have greater effects than conventional treadmill training (TT) in neurological diseases such as Parkinson's disease (PD). The aim of this study was to evaluate the effects of different percentages of BWSTT on gait, balance,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific and Technological Research Council of Turkey
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018238/ https://www.ncbi.nlm.nih.gov/pubmed/31292107 http://dx.doi.org/10.3906/sag-1812-57 |
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author | ATAN, Tuğba ÖZYEMİŞCİ TAŞKIRAN, Özden BORA TOKÇAER, Ayşe KAYMAK KARATAŞ, Gülçin KARAKUŞ ÇALIŞKAN, Aslı KARAOĞLAN, Belgin |
author_facet | ATAN, Tuğba ÖZYEMİŞCİ TAŞKIRAN, Özden BORA TOKÇAER, Ayşe KAYMAK KARATAŞ, Gülçin KARAKUŞ ÇALIŞKAN, Aslı KARAOĞLAN, Belgin |
author_sort | ATAN, Tuğba |
collection | PubMed |
description | BACKGROUND/AIM: Body weight-supported treadmill training (BWSTT) might have greater effects than conventional treadmill training (TT) in neurological diseases such as Parkinson's disease (PD). The aim of this study was to evaluate the effects of different percentages of BWSTT on gait, balance, quality of life, and fatigue in PD. MATERIALS AND METHODS: Thirty-five patients with moderate to advanced PD were randomized into three BWSTT groups according to the supported percentage of body weight: 0% BWSTT (control group; unsupported TT), 10% BWSTT, or 20% BWSTT. Five patients were excluded due to early discharge and 30 patients completed BWSTT sessions lasting 30 min, 5 days a week, for 6 weeks during their inpatient rehabilitation stay. The primary outcome was 6-min walk distance (6MWD). Secondary outcomes were Unified Parkinson's Disease Rating Scale (UPDRS), Berg Balance Scale (BBS), Nottingham Health Profile (NHP), Fatigue Impact Scale, and Fatigue Severity Scale scores. Measurements were performed before and after the training. RESULTS: The unsupported TT group demonstrated no significant improvement in the outcome measures after a 6-week training except for BBS and NHP emotional subscores. Moreover, the NHP pain subscore increased in the unsupported TT group after training. The 10% and 20% supported BWSTT groups demonstrated significant improvements in 6MWD (P = 0.004 and P < 0.001, respectively), UPDRS - motor score (P = 0.012 and P = 0.005, respectively), NHP pain subscore (P = 0.003 and P = 0.002, respectively), and fatigue (P = 0.005 for both) after training. The 20% BWSTT provided the highest improvement in balance among the three groups (P < 0.001) and greater relief of fatigue than 10% BWSTT (P = 0.002). CONCLUSION: Six weeks of BWSTT improved walking distance and balance ability, relieved fatigue, and additionally reduced pain in patients with moderate to advanced PD. |
format | Online Article Text |
id | pubmed-7018238 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Scientific and Technological Research Council of Turkey |
record_format | MEDLINE/PubMed |
spelling | pubmed-70182382020-03-23 Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial ATAN, Tuğba ÖZYEMİŞCİ TAŞKIRAN, Özden BORA TOKÇAER, Ayşe KAYMAK KARATAŞ, Gülçin KARAKUŞ ÇALIŞKAN, Aslı KARAOĞLAN, Belgin Turk J Med Sci Article BACKGROUND/AIM: Body weight-supported treadmill training (BWSTT) might have greater effects than conventional treadmill training (TT) in neurological diseases such as Parkinson's disease (PD). The aim of this study was to evaluate the effects of different percentages of BWSTT on gait, balance, quality of life, and fatigue in PD. MATERIALS AND METHODS: Thirty-five patients with moderate to advanced PD were randomized into three BWSTT groups according to the supported percentage of body weight: 0% BWSTT (control group; unsupported TT), 10% BWSTT, or 20% BWSTT. Five patients were excluded due to early discharge and 30 patients completed BWSTT sessions lasting 30 min, 5 days a week, for 6 weeks during their inpatient rehabilitation stay. The primary outcome was 6-min walk distance (6MWD). Secondary outcomes were Unified Parkinson's Disease Rating Scale (UPDRS), Berg Balance Scale (BBS), Nottingham Health Profile (NHP), Fatigue Impact Scale, and Fatigue Severity Scale scores. Measurements were performed before and after the training. RESULTS: The unsupported TT group demonstrated no significant improvement in the outcome measures after a 6-week training except for BBS and NHP emotional subscores. Moreover, the NHP pain subscore increased in the unsupported TT group after training. The 10% and 20% supported BWSTT groups demonstrated significant improvements in 6MWD (P = 0.004 and P < 0.001, respectively), UPDRS - motor score (P = 0.012 and P = 0.005, respectively), NHP pain subscore (P = 0.003 and P = 0.002, respectively), and fatigue (P = 0.005 for both) after training. The 20% BWSTT provided the highest improvement in balance among the three groups (P < 0.001) and greater relief of fatigue than 10% BWSTT (P = 0.002). CONCLUSION: Six weeks of BWSTT improved walking distance and balance ability, relieved fatigue, and additionally reduced pain in patients with moderate to advanced PD. The Scientific and Technological Research Council of Turkey 2019-08-08 /pmc/articles/PMC7018238/ /pubmed/31292107 http://dx.doi.org/10.3906/sag-1812-57 Text en Copyright © 2019 The Author(s) This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Article ATAN, Tuğba ÖZYEMİŞCİ TAŞKIRAN, Özden BORA TOKÇAER, Ayşe KAYMAK KARATAŞ, Gülçin KARAKUŞ ÇALIŞKAN, Aslı KARAOĞLAN, Belgin Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial |
title | Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial |
title_full | Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial |
title_fullStr | Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial |
title_full_unstemmed | Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial |
title_short | Effects of different percentages of body weight-supported treadmill training in Parkinson's disease: a double-blind randomized controlled trial |
title_sort | effects of different percentages of body weight-supported treadmill training in parkinson's disease: a double-blind randomized controlled trial |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018238/ https://www.ncbi.nlm.nih.gov/pubmed/31292107 http://dx.doi.org/10.3906/sag-1812-57 |
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