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Serum zinc levels in seborrheic dermatitis: a case-control study
BACKGROUND/AIM: Malassezia colonization, sebaceous gland activity, hormones, immune system defects, environmental factors, and the interactions between these factors are thought to contribute to the pathogenesis of seborrheic dermatitis (SD). Zinc, an essential element, is involved in many biologica...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific and Technological Research Council of Turkey
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018314/ https://www.ncbi.nlm.nih.gov/pubmed/31651121 http://dx.doi.org/10.3906/sag-1906-72 |
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author | AKTAŞ KARABAY, Ezgi AKSU ÇERMAN, Aslı |
author_facet | AKTAŞ KARABAY, Ezgi AKSU ÇERMAN, Aslı |
author_sort | AKTAŞ KARABAY, Ezgi |
collection | PubMed |
description | BACKGROUND/AIM: Malassezia colonization, sebaceous gland activity, hormones, immune system defects, environmental factors, and the interactions between these factors are thought to contribute to the pathogenesis of seborrheic dermatitis (SD). Zinc, an essential element, is involved in many biological processes including the ones that contribute to the development of SD. The aim of this study is to evaluate serum zinc levels in patients with SD. MATERIALS AND METHODS: Forty-three patients with SD and 41 healthy controls were enrolled in the study. Disease activity was assessed by the Seborrheic Dermatitis Area and Severity Index by a single dermatologist. Serum zinc levels of all subjects were evaluated. RESULTS: Statistically significantly lower serum zinc levels were noted in SD patients than in the control group (79.16 ± 12.17 vs. 84.88 ± 13.59, respectively; P = 0.045). CONCLUSION: The results of the study demonstrated that patients who had SD had lower levels of serum zinc levels than healthy subjects. |
format | Online Article Text |
id | pubmed-7018314 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Scientific and Technological Research Council of Turkey |
record_format | MEDLINE/PubMed |
spelling | pubmed-70183142020-03-23 Serum zinc levels in seborrheic dermatitis: a case-control study AKTAŞ KARABAY, Ezgi AKSU ÇERMAN, Aslı Turk J Med Sci Article BACKGROUND/AIM: Malassezia colonization, sebaceous gland activity, hormones, immune system defects, environmental factors, and the interactions between these factors are thought to contribute to the pathogenesis of seborrheic dermatitis (SD). Zinc, an essential element, is involved in many biological processes including the ones that contribute to the development of SD. The aim of this study is to evaluate serum zinc levels in patients with SD. MATERIALS AND METHODS: Forty-three patients with SD and 41 healthy controls were enrolled in the study. Disease activity was assessed by the Seborrheic Dermatitis Area and Severity Index by a single dermatologist. Serum zinc levels of all subjects were evaluated. RESULTS: Statistically significantly lower serum zinc levels were noted in SD patients than in the control group (79.16 ± 12.17 vs. 84.88 ± 13.59, respectively; P = 0.045). CONCLUSION: The results of the study demonstrated that patients who had SD had lower levels of serum zinc levels than healthy subjects. The Scientific and Technological Research Council of Turkey 2019-10-24 /pmc/articles/PMC7018314/ /pubmed/31651121 http://dx.doi.org/10.3906/sag-1906-72 Text en Copyright © 2019 The Author(s) This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Article AKTAŞ KARABAY, Ezgi AKSU ÇERMAN, Aslı Serum zinc levels in seborrheic dermatitis: a case-control study |
title | Serum zinc levels in seborrheic dermatitis: a case-control study |
title_full | Serum zinc levels in seborrheic dermatitis: a case-control study |
title_fullStr | Serum zinc levels in seborrheic dermatitis: a case-control study |
title_full_unstemmed | Serum zinc levels in seborrheic dermatitis: a case-control study |
title_short | Serum zinc levels in seborrheic dermatitis: a case-control study |
title_sort | serum zinc levels in seborrheic dermatitis: a case-control study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018314/ https://www.ncbi.nlm.nih.gov/pubmed/31651121 http://dx.doi.org/10.3906/sag-1906-72 |
work_keys_str_mv | AT aktaskarabayezgi serumzinclevelsinseborrheicdermatitisacasecontrolstudy AT aksucermanaslı serumzinclevelsinseborrheicdermatitisacasecontrolstudy |