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Serum zinc levels in seborrheic dermatitis: a case-control study

BACKGROUND/AIM: Malassezia colonization, sebaceous gland activity, hormones, immune system defects, environmental factors, and the interactions between these factors are thought to contribute to the pathogenesis of seborrheic dermatitis (SD). Zinc, an essential element, is involved in many biologica...

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Autores principales: AKTAŞ KARABAY, Ezgi, AKSU ÇERMAN, Aslı
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018314/
https://www.ncbi.nlm.nih.gov/pubmed/31651121
http://dx.doi.org/10.3906/sag-1906-72
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author AKTAŞ KARABAY, Ezgi
AKSU ÇERMAN, Aslı
author_facet AKTAŞ KARABAY, Ezgi
AKSU ÇERMAN, Aslı
author_sort AKTAŞ KARABAY, Ezgi
collection PubMed
description BACKGROUND/AIM: Malassezia colonization, sebaceous gland activity, hormones, immune system defects, environmental factors, and the interactions between these factors are thought to contribute to the pathogenesis of seborrheic dermatitis (SD). Zinc, an essential element, is involved in many biological processes including the ones that contribute to the development of SD. The aim of this study is to evaluate serum zinc levels in patients with SD. MATERIALS AND METHODS: Forty-three patients with SD and 41 healthy controls were enrolled in the study. Disease activity was assessed by the Seborrheic Dermatitis Area and Severity Index by a single dermatologist. Serum zinc levels of all subjects were evaluated. RESULTS: Statistically significantly lower serum zinc levels were noted in SD patients than in the control group (79.16 ± 12.17 vs. 84.88 ± 13.59, respectively; P = 0.045). CONCLUSION: The results of the study demonstrated that patients who had SD had lower levels of serum zinc levels than healthy subjects.
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spelling pubmed-70183142020-03-23 Serum zinc levels in seborrheic dermatitis: a case-control study AKTAŞ KARABAY, Ezgi AKSU ÇERMAN, Aslı Turk J Med Sci Article BACKGROUND/AIM: Malassezia colonization, sebaceous gland activity, hormones, immune system defects, environmental factors, and the interactions between these factors are thought to contribute to the pathogenesis of seborrheic dermatitis (SD). Zinc, an essential element, is involved in many biological processes including the ones that contribute to the development of SD. The aim of this study is to evaluate serum zinc levels in patients with SD. MATERIALS AND METHODS: Forty-three patients with SD and 41 healthy controls were enrolled in the study. Disease activity was assessed by the Seborrheic Dermatitis Area and Severity Index by a single dermatologist. Serum zinc levels of all subjects were evaluated. RESULTS: Statistically significantly lower serum zinc levels were noted in SD patients than in the control group (79.16 ± 12.17 vs. 84.88 ± 13.59, respectively; P = 0.045). CONCLUSION: The results of the study demonstrated that patients who had SD had lower levels of serum zinc levels than healthy subjects. The Scientific and Technological Research Council of Turkey 2019-10-24 /pmc/articles/PMC7018314/ /pubmed/31651121 http://dx.doi.org/10.3906/sag-1906-72 Text en Copyright © 2019 The Author(s) This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Article
AKTAŞ KARABAY, Ezgi
AKSU ÇERMAN, Aslı
Serum zinc levels in seborrheic dermatitis: a case-control study
title Serum zinc levels in seborrheic dermatitis: a case-control study
title_full Serum zinc levels in seborrheic dermatitis: a case-control study
title_fullStr Serum zinc levels in seborrheic dermatitis: a case-control study
title_full_unstemmed Serum zinc levels in seborrheic dermatitis: a case-control study
title_short Serum zinc levels in seborrheic dermatitis: a case-control study
title_sort serum zinc levels in seborrheic dermatitis: a case-control study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018314/
https://www.ncbi.nlm.nih.gov/pubmed/31651121
http://dx.doi.org/10.3906/sag-1906-72
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