Nodal β spectrins are required to maintain Na(+) channel clustering and axon integrity

Clustered ion channels at nodes of Ranvier are critical for fast action potential propagation in myelinated axons. Axon-glia interactions converge on ankyrin and spectrin cytoskeletal proteins to cluster nodal Na(+) channels during development. However, how nodal ion channel clusters are maintained...

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Detalles Bibliográficos
Autores principales: Liu, Cheng-Hsin, Stevens, Sharon R, Teliska, Lindsay H, Stankewich, Michael, Mohler, Peter J, Hund, Thomas J, Rasband, Matthew N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018506/
https://www.ncbi.nlm.nih.gov/pubmed/32052742
http://dx.doi.org/10.7554/eLife.52378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018506/
https://www.ncbi.nlm.nih.gov/pubmed/32052742
http://dx.doi.org/10.7554/eLife.52378

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