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The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability
Microtubules are cytoskeletal polymers whose function depends on their property to switch between states of growth and shrinkage. Growing microtubules are thought to be stabilized by a GTP cap at their ends. The nature of this cap, however, is still poorly understood. End Binding proteins (EBs) recr...
Autores principales: | Roostalu, Johanna, Thomas, Claire, Cade, Nicholas Ian, Kunzelmann, Simone, Taylor, Ian A, Surrey, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018511/ https://www.ncbi.nlm.nih.gov/pubmed/32053491 http://dx.doi.org/10.7554/eLife.51992 |
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