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Structure of the human BBSome core complex

The BBSome is a heterooctameric protein complex that plays a central role in primary cilia homeostasis. Its malfunction causes the severe ciliopathy Bardet-Biedl syndrome (BBS). The complex acts as a cargo adapter that recognizes signaling proteins such as GPCRs and links them to the intraflagellar...

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Detalles Bibliográficos
Autores principales:	Klink, Björn Udo, Gatsogiannis, Christos, Hofnagel, Oliver, Wittinghofer, Alfred, Raunser, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018512/ https://www.ncbi.nlm.nih.gov/pubmed/31951201 http://dx.doi.org/10.7554/eLife.53910

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