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Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae
Poor penetration through the outer membrane (OM) of Gram-negative bacteria is a major barrier of antibiotic development. While β-lactam antibiotics are commonly used against Klebsiella pneumoniae and Enterobacter cloacae, there are limited data on OM permeability especially in K. pneumoniae. Here, w...
Autores principales: | Kim, Tae Hwan, Tao, Xun, Moya, Bartolome, Jiao, Yuanyuan, Basso, Kari B., Zhou, Jieqiang, Lang, Yinzhi, Sutaria, Dhruvitkumar S., Zavascki, Alexandre P., Barth, Afonso L., Reeve, Stephanie M., Schweizer, Herbert P., Deveson Lucas, Deanna, Boyce, John D., Bonomo, Robert A., Lee, Richard E., Shin, Beom Soo, Louie, Arnold, Drusano, George L., Bulitta, Jürgen B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018653/ https://www.ncbi.nlm.nih.gov/pubmed/32047131 http://dx.doi.org/10.1128/mBio.03189-19 |
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