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The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistance

Ovarian cancer (OVCA) is the most lethal gynecological cancer, due predominantly to late presentation, high recurrence rate and common chemoresistance development. The expression of the actin-associated protein cytosolic gelsolin (GSN) regulates the gynecological cancer cell fate resulting in dysreg...

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Detalles Bibliográficos
Autores principales: Asare-Werehene, Meshach, Nakka, Kiran, Reunov, Arkadiy, Chiu, Chen-Tzu, Lee, Wei-Ting, Abedini, Mohammad R., Wang, Pei-Wen, Shieh, Dar-Bin, Dilworth, F. Jeffrey, Carmona, Euridice, Le, Tien, Mes-Masson, Anne-Marie, Burger, Dylan, Tsang, Benjamin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018662/
https://www.ncbi.nlm.nih.gov/pubmed/31700155
http://dx.doi.org/10.1038/s41388-019-1087-9