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The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistance
Ovarian cancer (OVCA) is the most lethal gynecological cancer, due predominantly to late presentation, high recurrence rate and common chemoresistance development. The expression of the actin-associated protein cytosolic gelsolin (GSN) regulates the gynecological cancer cell fate resulting in dysreg...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018662/ https://www.ncbi.nlm.nih.gov/pubmed/31700155 http://dx.doi.org/10.1038/s41388-019-1087-9 |