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TTX-Resistant Sodium Channels Functionally Separate Silent From Polymodal C-nociceptors

Pronounced activity-dependent slowing of conduction has been used to characterize mechano-insensitive, “silent” nociceptors and might be due to high expression of Na(V)1.8 and could, therefore, be characterized by their tetrodotoxin-resistance (TTX-r). Nociceptor-class specific differences in action...

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Detalles Bibliográficos
Autores principales: Jonas, Robin, Prato, Vincenzo, Lechner, Stefan G., Groen, Gerbrand, Obreja, Otilia, Werland, Fiona, Rukwied, Roman, Klusch, Andreas, Petersen, Marlen, Carr, Richard W., Schmelz, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018684/
https://www.ncbi.nlm.nih.gov/pubmed/32116559
http://dx.doi.org/10.3389/fncel.2020.00013