TAK1 signaling regulates p53 through a mechanism involving ribosomal stress

Triple-negative breast cancer (TNBC) is among the most aggressive forms of breast cancer with limited therapeutic options. TAK1 is implicated in aggressive behavior of TNBC, while means are not fully understood. Here, we report that pharmacological blockade of TAK1 signaling hampered ribosome biogen...

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Detalles Bibliográficos
Autores principales: Zonneville, Justin, Wong, Vincent, Limoge, Michelle, Nikiforov, Mikhail, Bakin, Andrei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018718/
https://www.ncbi.nlm.nih.gov/pubmed/32054925
http://dx.doi.org/10.1038/s41598-020-59340-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018718/
https://www.ncbi.nlm.nih.gov/pubmed/32054925
http://dx.doi.org/10.1038/s41598-020-59340-5

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