PERK-mediated expression of peptidylglycine α-amidating monooxygenase supports angiogenesis in glioblastoma

PKR-like kinase (PERK) plays a significant role in inducing angiogenesis in various cancer types including glioblastoma. By proteomics analysis of the conditioned medium from a glioblastoma cell line treated with a PERK inhibitor, we showed that peptidylglycine α-amidating monooxygenase (PAM) expres...

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Detalles Bibliográficos
Autores principales: Soni, Himanshu, Bode, Julia, Nguyen, Chi D. L., Puccio, Laura, Neßling, Michelle, Piro, Rosario M., Bub, Jonas, Phillips, Emma, Ahrends, Robert, Eipper, Betty A., Tews, Björn, Goidts, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018722/
https://www.ncbi.nlm.nih.gov/pubmed/32054826
http://dx.doi.org/10.1038/s41389-020-0201-8

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