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The Dopamine D5 receptor contributes to activation of cholinergic interneurons during L-DOPA induced dyskinesia
The dopamine D5 receptor (D5R) is a Gα(s)-coupled dopamine receptor belonging to the dopamine D1-like receptor family. Together with the dopamine D2 receptor it is highly expressed in striatal cholinergic interneurons and therefore is poised to be a positive regulator of cholinergic activity in resp...
Autores principales: | Castello, Julia, Cortés, Marisol, Malave, Lauren, Kottmann, Andreas, Sibley, David R., Friedman, Eitan, Rebholz, Heike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018760/ https://www.ncbi.nlm.nih.gov/pubmed/32054879 http://dx.doi.org/10.1038/s41598-020-59011-5 |
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