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The Dopamine D5 receptor contributes to activation of cholinergic interneurons during L-DOPA induced dyskinesia

The dopamine D5 receptor (D5R) is a Gα(s)-coupled dopamine receptor belonging to the dopamine D1-like receptor family. Together with the dopamine D2 receptor it is highly expressed in striatal cholinergic interneurons and therefore is poised to be a positive regulator of cholinergic activity in resp...

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Detalles Bibliográficos
Autores principales: Castello, Julia, Cortés, Marisol, Malave, Lauren, Kottmann, Andreas, Sibley, David R., Friedman, Eitan, Rebholz, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018760/
https://www.ncbi.nlm.nih.gov/pubmed/32054879
http://dx.doi.org/10.1038/s41598-020-59011-5

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