Antagonizing circRNA_002581–miR-122–CPEB1 axis alleviates NASH through restoring PTEN–AMPK–mTOR pathway regulated autophagy

Circular RNAs (circRNAs) have been shown to play critical roles in cancer biology, but their functions in nonalcoholic steatohepatitis (NASH) remain unexplored. Full length of circRNA_002581 was amplified and sequenced, followed by RNA immunoprecipitation, RNA-Fluorescence in Situ Hybridization and...

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Detalles Bibliográficos
Autores principales: Jin, Xi, Gao, Jianguo, Zheng, Ruoheng, Yu, Mosang, Ren, Yue, Yan, Tianlian, Huang, Yue, Li, Youming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018772/
https://www.ncbi.nlm.nih.gov/pubmed/32054840
http://dx.doi.org/10.1038/s41419-020-2293-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018772/
https://www.ncbi.nlm.nih.gov/pubmed/32054840
http://dx.doi.org/10.1038/s41419-020-2293-7

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