Blockade of the renin-angiotensin system suppresses hydroxyl radical production in the rat striatum during carbon monoxide poisoning

Oxidative stress has been suggested to play a role in brain damage during carbon monoxide (CO) poisoning. Severe poisoning induced by CO at 3000 ppm, but not 1000 ppm, enhances hydroxyl radical (˙OH) production in the rat striatum, which might be mediated by NADPH oxidase (NOX) activation associated...

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Detalles Bibliográficos
Autores principales: Hara, Shuichi, Kobayashi, Masamune, Kuriiwa, Fumi, Mizukami, Hajime, Mukai, Toshiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018774/
https://www.ncbi.nlm.nih.gov/pubmed/32054947
http://dx.doi.org/10.1038/s41598-020-59377-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018774/
https://www.ncbi.nlm.nih.gov/pubmed/32054947
http://dx.doi.org/10.1038/s41598-020-59377-6

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