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Conversion of chemical to mechanical energy by the nucleotide binding domains of ABCB1

P-glycoprotein (ABCB1) is an important component of barrier tissues that extrudes a wide range of chemically unrelated compounds. ABCB1 consists of two transmembrane domains forming the substrate binding and translocation domain, and of two cytoplasmic nucleotide binding domains (NBDs) that provide...

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Detalles Bibliográficos
Autores principales: Szöllősi, Dániel, Chiba, Peter, Szakacs, Gergely, Stockner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018802/
https://www.ncbi.nlm.nih.gov/pubmed/32054924
http://dx.doi.org/10.1038/s41598-020-59403-7