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FMN reduces Amyloid-β toxicity in yeast by regulating redox status and cellular metabolism

Alzheimer’s disease (AD) is defined by progressive neurodegeneration, with oligomerization and aggregation of amyloid-β peptides (Aβ) playing a pivotal role in its pathogenesis. In recent years, the yeast Saccharomyces cerevisiae has been successfully used to clarify the roles of different human pro...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Ji, Boyang, Hao, Xinxin, Li, Xiaowei, Eisele, Frederik, Nyström, Thomas, Petranovic, Dina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018843/
https://www.ncbi.nlm.nih.gov/pubmed/32054832
http://dx.doi.org/10.1038/s41467-020-14525-4

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