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Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation
Glycosylphosphatidylinositol (GPI)-anchored proteins and glycosphingolipids interact with each other in the mammalian plasma membranes, forming dynamic microdomains. How their interaction starts in the cells has been unclear. Here, based on a genome-wide CRISPR-Cas9 genetic screen for genes required...
Autores principales: | Wang, Yicheng, Maeda, Yusuke, Liu, Yi-Shi, Takada, Yoko, Ninomiya, Akinori, Hirata, Tetsuya, Fujita, Morihisa, Murakami, Yoshiko, Kinoshita, Taroh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018848/ https://www.ncbi.nlm.nih.gov/pubmed/32054864 http://dx.doi.org/10.1038/s41467-020-14678-2 |
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