Allele-specific miRNA-binding analysis identifies candidate target genes for breast cancer risk

Most breast cancer (BC) risk-associated single-nucleotide polymorphisms (raSNPs) identified in genome-wide association studies (GWAS) are believed to cis-regulate the expression of genes. We hypothesise that cis-regulatory variants contributing to disease risk may be affecting microRNA (miRNA) genes...

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Detalles Bibliográficos
Autores principales: Jacinta-Fernandes, Ana, Xavier, Joana M., Magno, Ramiro, Lage, Joel G., Maia, Ana-Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018948/
https://www.ncbi.nlm.nih.gov/pubmed/32128252
http://dx.doi.org/10.1038/s41525-019-0112-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018948/
https://www.ncbi.nlm.nih.gov/pubmed/32128252
http://dx.doi.org/10.1038/s41525-019-0112-9

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