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Allele-specific miRNA-binding analysis identifies candidate target genes for breast cancer risk
Most breast cancer (BC) risk-associated single-nucleotide polymorphisms (raSNPs) identified in genome-wide association studies (GWAS) are believed to cis-regulate the expression of genes. We hypothesise that cis-regulatory variants contributing to disease risk may be affecting microRNA (miRNA) genes...
Autores principales: | Jacinta-Fernandes, Ana, Xavier, Joana M., Magno, Ramiro, Lage, Joel G., Maia, Ana-Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018948/ https://www.ncbi.nlm.nih.gov/pubmed/32128252 http://dx.doi.org/10.1038/s41525-019-0112-9 |
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