Cynomolgus Monkeys With Spontaneous Type-2-Diabetes-Mellitus-Like Pathology Develop Alpha-Synuclein Alterations Reminiscent of Prodromal Parkinson’s Disease and Related Diseases

Available evidence suggests that diabetes mellitus (DM) is a non-genetic risk factor for Parkinson’s disease (PD). PD and DM have shared similarities in pathogenetic mechanisms, including age, environmental factors, inflammatory reaction, and protein aggregation, etc. α-Synuclein is the primary prot...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Guo, Chuang, Yuan, Lin, Li, Wen, Wang, Zhan-You, Yue, Feng, Li, Jia-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019001/
https://www.ncbi.nlm.nih.gov/pubmed/32116510
http://dx.doi.org/10.3389/fnins.2020.00063

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