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Crucial Involvement of IL-6 in Thrombus Resolution in Mice via Macrophage Recruitment and the Induction of Proteolytic Enzymes

After the ligation of the inferior vena cava (IVC) of wild-type (WT) mice, venous thrombi formed and grew progressively until 5 days and resolved thereafter. Concomitantly, intrathrombotic gene expression of Il6 was enhanced later than 5 days after IVC ligation. IL-6 protein expression was detected...

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Detalles Bibliográficos
Autores principales: Nosaka, Mizuho, Ishida, Yuko, Kimura, Akihiko, Kuninaka, Yumi, Taruya, Akira, Ozaki, Mitsunori, Tanaka, Atushi, Mukaida, Naofumi, Kondo, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019028/
https://www.ncbi.nlm.nih.gov/pubmed/32117207
http://dx.doi.org/10.3389/fimmu.2019.03150