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Crucial Involvement of IL-6 in Thrombus Resolution in Mice via Macrophage Recruitment and the Induction of Proteolytic Enzymes
After the ligation of the inferior vena cava (IVC) of wild-type (WT) mice, venous thrombi formed and grew progressively until 5 days and resolved thereafter. Concomitantly, intrathrombotic gene expression of Il6 was enhanced later than 5 days after IVC ligation. IL-6 protein expression was detected...
Autores principales: | Nosaka, Mizuho, Ishida, Yuko, Kimura, Akihiko, Kuninaka, Yumi, Taruya, Akira, Ozaki, Mitsunori, Tanaka, Atushi, Mukaida, Naofumi, Kondo, Toshikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019028/ https://www.ncbi.nlm.nih.gov/pubmed/32117207 http://dx.doi.org/10.3389/fimmu.2019.03150 |
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