IC261, a specific inhibitor of CK1δ/ε, promotes aerobic glycolysis through p53-dependent mechanisms in colon cancer

Casein kinase 1δ (CK1δ) and casein kinase 1ε (CK1ε) have been proposed to be involved in DNA replication, differentiation and apoptosis, thus participating in the regulation of tumorigenesis. However, their functions in colon cancer and the underlying mechanism remain unclear. Here, we found that th...

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Detalles Bibliográficos
Autores principales: Liu, Min, Hu, Yuhan, Lu, Shuya, Lu, Manman, Li, Jingsong, Chang, Haimin, Jia, Huijie, Zhou, Min, Ren, Feng, Zhong, Jiateng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019134/
https://www.ncbi.nlm.nih.gov/pubmed/32071557
http://dx.doi.org/10.7150/ijbs.40960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019134/
https://www.ncbi.nlm.nih.gov/pubmed/32071557
http://dx.doi.org/10.7150/ijbs.40960

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