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IC261, a specific inhibitor of CK1δ/ε, promotes aerobic glycolysis through p53-dependent mechanisms in colon cancer
Casein kinase 1δ (CK1δ) and casein kinase 1ε (CK1ε) have been proposed to be involved in DNA replication, differentiation and apoptosis, thus participating in the regulation of tumorigenesis. However, their functions in colon cancer and the underlying mechanism remain unclear. Here, we found that th...
Autores principales: | Liu, Min, Hu, Yuhan, Lu, Shuya, Lu, Manman, Li, Jingsong, Chang, Haimin, Jia, Huijie, Zhou, Min, Ren, Feng, Zhong, Jiateng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019134/ https://www.ncbi.nlm.nih.gov/pubmed/32071557 http://dx.doi.org/10.7150/ijbs.40960 |
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