CCBE1 promotes tumor lymphangiogenesis and is negatively regulated by TGFβ signaling in colorectal cancer

Collagen and calcium-binding EGF domain-1 (CCBE1) is essential for lymphatic vascular development as it promotes vascular endothelial growth factor C (VEGFC) proteolysis. A recent study reported that CCBE1 was overexpressed in epithelial colorectal cancer (CRC) cells; however, the role of CCBE1 in t...

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Detalles Bibliográficos
Autores principales: Song, Jinglue, Chen, Wei, Cui, Xuewei, Huang, Zhenyu, Wen, Dongpeng, Yang, Yili, Yu, Wei, Cui, Long, Liu, Chen-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019157/
https://www.ncbi.nlm.nih.gov/pubmed/32089745
http://dx.doi.org/10.7150/thno.39740

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