Cargando…

19q13 KRAB zinc-finger protein ZNF471 activates MAPK10/JNK3 signaling but is frequently silenced by promoter CpG methylation in esophageal cancer

Zinc-finger proteins (ZFPs) are the largest transcription factor family in mammals, involved in the regulation of multiple physiologic processes including cell differentiation, proliferation, apoptosis and neoplastic transformation. Approximately one-third of ZFPs are Krüppel-associated box domain (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Ran, Xiang, Tingxiu, Tang, Jun, Peng, Weiyan, Luo, Jie, Li, Lili, Qiu, Zhu, Tan, Yiqing, Ye, Lin, Zhang, Min, Ren, Guosheng, Tao, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019175/ https://www.ncbi.nlm.nih.gov/pubmed/32089740 http://dx.doi.org/10.7150/thno.35861

Ejemplares similares

KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer
por: Pei, Lijiao, et al.
Publicado: (2018)

The novel 19q13 KRAB zinc-finger tumour suppressor ZNF382 is frequently methylated in oesophageal squamous cell carcinoma and antagonises Wnt/β-catenin signalling
por: Zhang, Chong, et al.
Publicado: (2018)

Zinc Fingers Function Cooperatively with KRAB Domain for Nuclear Localization of KRAB-Containing Zinc Finger Proteins
por: Wang, Wei, et al.
Publicado: (2014)

KRAB-containing zinc-finger repressor proteins
por: Urrutia, Raul
Publicado: (2003)

KRAB zinc finger protein ZNF676 controls the transcriptional influence of LTR12-related endogenous retrovirus sequences
por: Iouranova, Alexandra, et al.
Publicado: (2022)

The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses
por: Wolf, Gernot, et al.
Publicado: (2015)

DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells
por: Xiang, Tingxiu, et al.
Publicado: (2016)

The tumor suppressor Zinc finger protein 471 suppresses breast cancer growth and metastasis through inhibiting AKT and Wnt/β-catenin signaling
por: Tao, Chunfang, et al.
Publicado: (2020)

Correction to: The tumor suppressor Zinc finger protein 471 suppresses breast cancer growth and metastasis through inhibiting AKT and Wnt/β‑catenin signaling
por: Tao, Chunfang, et al.
Publicado: (2022)

KRAB-Zinc Finger Protein ZNF268a Deficiency Attenuates the Virus-Induced Pro-Inflammatory Response by Preventing IKK Complex Assembly
por: Liu, Yi, et al.
Publicado: (2019)

Evolving imprinting control regions: KRAB zinc fingers hold the key
por: Juan, Aimee M., et al.
Publicado: (2019)

Genetic features and genomic targets of human KRAB-zinc finger proteins
por: de Tribolet-Hardy, Jonas, et al.
Publicado: (2023)

ZNF91 deletion in human embryonic stem cells leads to ectopic activation of SVA retrotransposons and up-regulation of KRAB zinc finger gene clusters
por: Haring, Nina L., et al.
Publicado: (2021)

The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification
por: Helleboid, Pierre‐Yves, et al.
Publicado: (2019)

KRAB zinc finger protein diversification drives mammalian interindividual methylation variability
por: Bertozzi, Tessa M., et al.
Publicado: (2020)

Molecular Analysis of ZNF71 KRAB in Non-Small-Cell Lung Cancer
por: Ye, Qing, et al.
Publicado: (2021)

The KRAB Domain of ZNF10 Guides the Identification of Specific Amino Acids That Transform the Ancestral KRAB-A-Related Domain Present in Human PRDM9 into a Canonical Modern KRAB-A Domain
por: Lorenz, Peter, et al.
Publicado: (2022)

KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions
por: Lupo, Angelo, et al.
Publicado: (2013)

KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
por: Wolf, Gernot, et al.
Publicado: (2020)

Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression
por: Ito, Jumpei, et al.
Publicado: (2020)

Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells
por: Chauvin, Anaïs, et al.
Publicado: (2022)

Structural Evolution of Gene Promoters Driven by Primate-Specific KRAB Zinc Finger Proteins
por: Farmiloe, Grace, et al.
Publicado: (2023)

The new 6q27 tumor suppressor DACT2, frequently silenced by CpG methylation, sensitizes nasopharyngeal cancer cells to paclitaxel and 5-FU toxicity via β-catenin/Cdc25c signaling and G2/M arrest
por: Zhang, Yan, et al.
Publicado: (2018)

Methylomic Analysis Identifies Frequent DNA Methylation of Zinc Finger Protein 582 (ZNF582) in Cervical Neoplasms
por: Huang, Rui-Lan, et al.
Publicado: (2012)

KRAB-zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution
por: Otsuka, Kai, et al.
Publicado: (2023)

Quantifying the arms race between LINE-1 and KRAB-zinc finger genes through TECookbook
por: Zuo, Zheng
Publicado: (2023)

DACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer
por: Yin, Xuedong, et al.
Publicado: (2013)

The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28
por: Murphy, Kristin E., et al.
Publicado: (2016)

Primate-restricted KRAB zinc finger proteins and target retrotransposons control gene expression in human neurons
por: Turelli, Priscilla, et al.
Publicado: (2020)

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons
por: Seah, Michelle K. Y., et al.
Publicado: (2019)

Mutant KRAS regulates transposable element RNA and innate immunity via KRAB zinc-finger genes
por: Reggiardo, Roman E., et al.
Publicado: (2022)

The expression signature of cancer‐associated KRAB‐ZNF factors identified in TCGA pan‐cancer transcriptomic data
por: Machnik, Marta, et al.
Publicado: (2019)

Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
por: Bae, Min Gyun, et al.
Publicado: (2016)

ZNF471 modulates EMT and functions as methylation regulated tumor suppressor with diagnostic and prognostic significance in cervical cancer
por: Bhat, Samatha, et al.
Publicado: (2021)

An evolutionary arms race between KRAB zinc finger genes 91/93 and SVA/L1 retrotransposons
por: Jacobs, Frank MJ, et al.
Publicado: (2014)

The mouse genome displays highly dynamic populations of KRAB-zinc finger protein genes and related genetic units
por: Kauzlaric, Annamaria, et al.
Publicado: (2017)

The 3p14.2 tumour suppressor ADAMTS9 is inactivated by promoter CpG methylation and inhibits tumour cell growth in breast cancer
por: Shao, Bianfei, et al.
Publicado: (2017)

Regulation of Adipocyte Differentiation by the Zinc Finger Protein ZNF638
por: Meruvu, Sunitha, et al.
Publicado: (2011)

Paired box 5 is a novel marker of breast cancers that is frequently downregulated by methylation
por: Li, Xia, et al.
Publicado: (2018)

KRAB–Zinc Finger Proteins and KAP1 Can Mediate Long-Range Transcriptional Repression through Heterochromatin Spreading
por: Groner, Anna C., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_redsrr9pqm9ieu6qbb0hcvpepc