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NOTCH4 maintains quiescent mesenchymal-like breast cancer stem cells via transcriptionally activating SLUG and GAS1 in triple-negative breast cancer
Rationale: NOTCH4 receptor has been implicated in triple-negative breast cancer (TNBC) development and breast cancer stem cell (BCSC) regulation. However, the potential of NOTCH4 as a BCSC marker and the underlying mechanisms remain unclear. Methods: In this study, we determined the expression and a...
Autores principales: | Zhou, Lei, Wang, Dong, Sheng, Dandan, Xu, Jiahui, Chen, Weilong, Qin, Yuanyuan, Du, Ruikai, Yang, Xiaoli, He, Xueyan, Xie, Ni, Liu, Suling, Zhang, Lixing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019177/ https://www.ncbi.nlm.nih.gov/pubmed/32104513 http://dx.doi.org/10.7150/thno.38875 |
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