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Genetic and Epigenetic Biomarkers of Immune Checkpoint Blockade Response

Checkpoint inhibitor therapy constitutes a promising cancer treatment strategy that targets the immune checkpoints to re-activate silenced T cell cytotoxicity. In recent pivotal trials, immune checkpoint blockade (ICB) demonstrated durable responses and acceptable toxicity, resulting in the regulato...

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Detalles Bibliográficos
Autores principales: Xiao, Qingyang, Nobre, André, Piñeiro, Pilar, Berciano-Guerrero, Miguel-Ángel, Alba, Emilio, Cobo, Manuel, Lauschke, Volker M., Barragán, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019273/
https://www.ncbi.nlm.nih.gov/pubmed/31968651
http://dx.doi.org/10.3390/jcm9010286

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