Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111

For highly pathogenic viruses, reporter assays that can be rapidly performed are critically needed to identify potentially functional mutations for further study under maximal containment (e.g., biosafety level 4 [BSL-4]). The Ebola virus nucleoprotein (NP) plays multiple essential roles during the...

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Detalles Bibliográficos
Autores principales: Lin, Aaron E., Diehl, William E., Cai, Yingyun, Finch, Courtney L., Akusobi, Chidiebere, Kirchdoerfer, Robert N., Bollinger, Laura, Schaffner, Stephen F., Brown, Elizabeth A., Saphire, Erica Ollmann, Andersen, Kristian G., Kuhn, Jens H., Luban, Jeremy, Sabeti, Pardis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019320/
https://www.ncbi.nlm.nih.gov/pubmed/31952352
http://dx.doi.org/10.3390/v12010105

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