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Role of Overweight and Obesity in Gastrointestinal Disease

The prevalence of obesity is increasing worldwide, leading to a severe impairment of overall health. Actually, obesity has been associated with several pathological conditions, causing an excess overall mortality. In particular, overweight and obesity are well known risk factors for a variety of gas...

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Detalles Bibliográficos
Autores principales: Emerenziani, Sara, Pier Luca Guarino, Michele, Trillo Asensio, Laura Maria, Altomare, Annamaria, Ribolsi, Mentore, Balestrieri, Paola, Cicala, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019431/
https://www.ncbi.nlm.nih.gov/pubmed/31906216
http://dx.doi.org/10.3390/nu12010111
Descripción
Sumario:The prevalence of obesity is increasing worldwide, leading to a severe impairment of overall health. Actually, obesity has been associated with several pathological conditions, causing an excess overall mortality. In particular, overweight and obesity are well known risk factors for a variety of gastrointestinal (GI) disorders i.e., functional GI disorders as well as, inflammatory bowel disease (IBD), pancreatitis, and GI cancer. The aim of the present review is to summarize the potential role of overweight and obesity in GI disease with particular focus on plausible biological mechanisms that could explain the association between obesity and GI disease based on the most recent evidence in the literature.