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Revealing solvent-dependent folding behavior of mycolic acids from Mycobacterium tuberculosis by advanced simulation analysis
Mycobacterium tuberculosis remains a persistent pathogen, partly due to its lipid rich cell wall, of which mycolic acids (MAs) are a major component. The fluidity and conformational flexibilities of different MAs in the bacterial cell wall significantly influence its properties, function, and observ...
Autores principales: | Groenewald, Wilma, Parra-Cruz, Ricardo A., Jäger, Christof M., Croft, Anna K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019640/ https://www.ncbi.nlm.nih.gov/pubmed/30762132 http://dx.doi.org/10.1007/s00894-019-3943-5 |
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