The Biogenetic Origin of the Biologically Active Naematolin of Hypholoma Species Involves an Unusual Sesquiterpene Synthase

Naematolin is a biologically active sesquiterpene produced by Hypholoma species. Low titres and complex structure constrain the exploitation of this secondary metabolite. Here, we de novo sequenced the H. fasciculare genome to identify a candidate biosynthetic gene cluster for production of naematol...

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Detalles Bibliográficos
Autores principales: Al-Salihi, Suhad A. A., Dao, Trong Tuan, Williams, Katherine, Bailey, Andy M., Foster, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019648/
https://www.ncbi.nlm.nih.gov/pubmed/31392585
http://dx.doi.org/10.1007/s12033-019-00199-x

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