Cargando…

Gut Microbiota Modulation by Dietary Barley Malt Melanoidins †

Melanoidins are the final Maillard reaction products (protein–carbohydrate complexes) produced in food by prolonged and intense heating. We assessed the impact of the consumption of melanoidins from barley malts on gut microbiota. Seventy-five mice were assigned into five groups, where the control g...

Descripción completa

Detalles Bibliográficos
Autores principales: Aljahdali, Nesreen, Gadonna-Widehem, Pascale, Anton, Pauline M., Carbonero, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019678/
https://www.ncbi.nlm.nih.gov/pubmed/31963440
http://dx.doi.org/10.3390/nu12010241
_version_ 1783497574660964352
author Aljahdali, Nesreen
Gadonna-Widehem, Pascale
Anton, Pauline M.
Carbonero, Franck
author_facet Aljahdali, Nesreen
Gadonna-Widehem, Pascale
Anton, Pauline M.
Carbonero, Franck
author_sort Aljahdali, Nesreen
collection PubMed
description Melanoidins are the final Maillard reaction products (protein–carbohydrate complexes) produced in food by prolonged and intense heating. We assessed the impact of the consumption of melanoidins from barley malts on gut microbiota. Seventy-five mice were assigned into five groups, where the control group consumed a non-melanoidin malt diet, and other groups received melanoidin-rich malts in increments of 25% up to 100% melanoidin malts. Feces were sampled at days 0, 1, 2, 3, 7, 14, and 21 and the microbiota was determined using V4 bacterial 16S rRNA amplicon sequencing and short-chain fatty acids (SCFA) by gas chromatography. Increased melanoidins was found to result in significantly divergent gut microbiota profiles and supported sustained SCFA production. The relative abundance of Dorea, Oscillibacter, and Alisitpes were decreased, while Lactobacillus, Parasutterella, Akkermansia, Bifidobacterium, and Barnesiella increased. Bifidobacterium spp. and Akkermansia spp. were significantly increased in mice consuming the highest melanoidin amounts, suggesting remarkable prebiotic potential.
format Online
Article
Text
id pubmed-7019678
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-70196782020-03-09 Gut Microbiota Modulation by Dietary Barley Malt Melanoidins † Aljahdali, Nesreen Gadonna-Widehem, Pascale Anton, Pauline M. Carbonero, Franck Nutrients Article Melanoidins are the final Maillard reaction products (protein–carbohydrate complexes) produced in food by prolonged and intense heating. We assessed the impact of the consumption of melanoidins from barley malts on gut microbiota. Seventy-five mice were assigned into five groups, where the control group consumed a non-melanoidin malt diet, and other groups received melanoidin-rich malts in increments of 25% up to 100% melanoidin malts. Feces were sampled at days 0, 1, 2, 3, 7, 14, and 21 and the microbiota was determined using V4 bacterial 16S rRNA amplicon sequencing and short-chain fatty acids (SCFA) by gas chromatography. Increased melanoidins was found to result in significantly divergent gut microbiota profiles and supported sustained SCFA production. The relative abundance of Dorea, Oscillibacter, and Alisitpes were decreased, while Lactobacillus, Parasutterella, Akkermansia, Bifidobacterium, and Barnesiella increased. Bifidobacterium spp. and Akkermansia spp. were significantly increased in mice consuming the highest melanoidin amounts, suggesting remarkable prebiotic potential. MDPI 2020-01-17 /pmc/articles/PMC7019678/ /pubmed/31963440 http://dx.doi.org/10.3390/nu12010241 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Aljahdali, Nesreen
Gadonna-Widehem, Pascale
Anton, Pauline M.
Carbonero, Franck
Gut Microbiota Modulation by Dietary Barley Malt Melanoidins †
title Gut Microbiota Modulation by Dietary Barley Malt Melanoidins †
title_full Gut Microbiota Modulation by Dietary Barley Malt Melanoidins †
title_fullStr Gut Microbiota Modulation by Dietary Barley Malt Melanoidins †
title_full_unstemmed Gut Microbiota Modulation by Dietary Barley Malt Melanoidins †
title_short Gut Microbiota Modulation by Dietary Barley Malt Melanoidins †
title_sort gut microbiota modulation by dietary barley malt melanoidins †
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019678/
https://www.ncbi.nlm.nih.gov/pubmed/31963440
http://dx.doi.org/10.3390/nu12010241
work_keys_str_mv AT aljahdalinesreen gutmicrobiotamodulationbydietarybarleymaltmelanoidins
AT gadonnawidehempascale gutmicrobiotamodulationbydietarybarleymaltmelanoidins
AT antonpaulinem gutmicrobiotamodulationbydietarybarleymaltmelanoidins
AT carbonerofranck gutmicrobiotamodulationbydietarybarleymaltmelanoidins