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Rho Kinase Activity, Connexin 40, and Atrial Fibrillation: Mechanistic Insights from End-Stage Renal Disease on Dialysis Patients

Evidence on cellular/molecular mechanisms leading to atrial fibrillation (AF) are scanty. Increased expression of Rho kinase (ROCK) and myosin-phosphatase-target subunit-1 (MYPT-1), ROCK activity’s marker, were shown in AF patients, which correlated with connexin 40 (Cx40) expression, membrane prote...

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Detalles Bibliográficos
Autores principales: Calò, Lorenzo A., Ravarotto, Verdiana, Bertoldi, Giovanni, Pagnin, Elisa, Rossi, Barbara, Rigato, Matteo, Davis, Paul A., Proietti, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019687/
https://www.ncbi.nlm.nih.gov/pubmed/31936157
http://dx.doi.org/10.3390/jcm9010165

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