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Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization

The objective of this study was to develop and explore a novel CD133-targeting immunotoxin (IT) for use in combination with the endosomal escape method photochemical internalization (PCI). scFvCD133/rGelonin was recombinantly constructed by fusing a gene (scFvCD133) encoding the scFv that targets bo...

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Detalles Bibliográficos
Autores principales:	Olsen, Cathrine Elisabeth, Cheung, Lawrence H., Weyergang, Anette, Berg, Kristian, Vallera, Daniel A., Rosenblum, Michael G., Selbo, Pål Kristian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019722/ https://www.ncbi.nlm.nih.gov/pubmed/31888091 http://dx.doi.org/10.3390/jcm9010068

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