Cargando…

Gender Differences in Obstructive Sleep Apnea: The Value of Sleep Questionnaires with a Separate Analysis of Cardiovascular Patients

Background: Gender affects the clinical presentation of obstructive sleep apnea (OSA). The classic OSA symptoms, such as sleepiness, snoring, and apnea, are not so frequent in women. Objectives: To evaluate possible gender differences in questionnaires used for OSA prediction, such as the Epworth Sl...

Descripción completa

Detalles Bibliográficos
Autores principales: Pataka, Athanasia, Kotoulas, Seraphim, Kalamaras, George, Schiza, Sofia, Sapalidis, Konstantinos, Giannakidis, Dimitirios, Michalopoulos, Nikolaos, Koulouris, Charilaos, Aidoni, Zoi, Amaniti, Aikaterini, Bouloukaki, Izoldi, Chatzopoulos, Evangelos, Romanidis, Konstantinos, Oikonomou, Panagoula, Steiropoulos, Paschalis, Trakada, Georgia, Vagionas, Anastasios, Ioannidis, Aris, Katsios, Iason Nikolaos, Goganau, Alexandru Marian, Zarogoulidis, Pavlos, Kosmidis, Christoforos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019723/
https://www.ncbi.nlm.nih.gov/pubmed/31947711
http://dx.doi.org/10.3390/jcm9010130
_version_ 1783497585271504896
author Pataka, Athanasia
Kotoulas, Seraphim
Kalamaras, George
Schiza, Sofia
Sapalidis, Konstantinos
Giannakidis, Dimitirios
Michalopoulos, Nikolaos
Koulouris, Charilaos
Aidoni, Zoi
Amaniti, Aikaterini
Bouloukaki, Izoldi
Chatzopoulos, Evangelos
Romanidis, Konstantinos
Oikonomou, Panagoula
Steiropoulos, Paschalis
Trakada, Georgia
Vagionas, Anastasios
Ioannidis, Aris
Katsios, Iason Nikolaos
Goganau, Alexandru Marian
Zarogoulidis, Pavlos
Kosmidis, Christoforos
author_facet Pataka, Athanasia
Kotoulas, Seraphim
Kalamaras, George
Schiza, Sofia
Sapalidis, Konstantinos
Giannakidis, Dimitirios
Michalopoulos, Nikolaos
Koulouris, Charilaos
Aidoni, Zoi
Amaniti, Aikaterini
Bouloukaki, Izoldi
Chatzopoulos, Evangelos
Romanidis, Konstantinos
Oikonomou, Panagoula
Steiropoulos, Paschalis
Trakada, Georgia
Vagionas, Anastasios
Ioannidis, Aris
Katsios, Iason Nikolaos
Goganau, Alexandru Marian
Zarogoulidis, Pavlos
Kosmidis, Christoforos
author_sort Pataka, Athanasia
collection PubMed
description Background: Gender affects the clinical presentation of obstructive sleep apnea (OSA). The classic OSA symptoms, such as sleepiness, snoring, and apnea, are not so frequent in women. Objectives: To evaluate possible gender differences in questionnaires used for OSA prediction, such as the Epworth Sleepiness Scale (ESS), STOP, STOP Bang (SB), Berlin Questionnaire (BQ), Athens Insomnia Scale (AIS), and Fatigue Scale (FS). Methods: 350 males were matched with 350 women referred to a sleep clinic, according to OSA severity. All responded to the questionnaires and underwent a sleep study. Cardiovascular disease (CVD) patients were separately analyzed. Results: ESS did not differ between genders. SB was higher in males, whereas STOP, BQ, AIS, and FS were higher in females. BQ presented the highest sensitivity in both genders, whereas STOP exhibited the highest specificity in males and ESS in females. AIS and FS were more sensitive and SB more specific in females, whereas BQ was more specific in males. For severe OSA, the predictive values of SB and BQ were almost similar for both genders; however AIS and FS were higher in women. CVD patients presented higher scores, independent of gender, except for AIS, which was higher in females. Conclusion: Gender-specific evaluation of questionnaires is necessary to prevent OSA under-diagnosis.
format Online
Article
Text
id pubmed-7019723
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-70197232020-03-09 Gender Differences in Obstructive Sleep Apnea: The Value of Sleep Questionnaires with a Separate Analysis of Cardiovascular Patients Pataka, Athanasia Kotoulas, Seraphim Kalamaras, George Schiza, Sofia Sapalidis, Konstantinos Giannakidis, Dimitirios Michalopoulos, Nikolaos Koulouris, Charilaos Aidoni, Zoi Amaniti, Aikaterini Bouloukaki, Izoldi Chatzopoulos, Evangelos Romanidis, Konstantinos Oikonomou, Panagoula Steiropoulos, Paschalis Trakada, Georgia Vagionas, Anastasios Ioannidis, Aris Katsios, Iason Nikolaos Goganau, Alexandru Marian Zarogoulidis, Pavlos Kosmidis, Christoforos J Clin Med Article Background: Gender affects the clinical presentation of obstructive sleep apnea (OSA). The classic OSA symptoms, such as sleepiness, snoring, and apnea, are not so frequent in women. Objectives: To evaluate possible gender differences in questionnaires used for OSA prediction, such as the Epworth Sleepiness Scale (ESS), STOP, STOP Bang (SB), Berlin Questionnaire (BQ), Athens Insomnia Scale (AIS), and Fatigue Scale (FS). Methods: 350 males were matched with 350 women referred to a sleep clinic, according to OSA severity. All responded to the questionnaires and underwent a sleep study. Cardiovascular disease (CVD) patients were separately analyzed. Results: ESS did not differ between genders. SB was higher in males, whereas STOP, BQ, AIS, and FS were higher in females. BQ presented the highest sensitivity in both genders, whereas STOP exhibited the highest specificity in males and ESS in females. AIS and FS were more sensitive and SB more specific in females, whereas BQ was more specific in males. For severe OSA, the predictive values of SB and BQ were almost similar for both genders; however AIS and FS were higher in women. CVD patients presented higher scores, independent of gender, except for AIS, which was higher in females. Conclusion: Gender-specific evaluation of questionnaires is necessary to prevent OSA under-diagnosis. MDPI 2020-01-03 /pmc/articles/PMC7019723/ /pubmed/31947711 http://dx.doi.org/10.3390/jcm9010130 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pataka, Athanasia
Kotoulas, Seraphim
Kalamaras, George
Schiza, Sofia
Sapalidis, Konstantinos
Giannakidis, Dimitirios
Michalopoulos, Nikolaos
Koulouris, Charilaos
Aidoni, Zoi
Amaniti, Aikaterini
Bouloukaki, Izoldi
Chatzopoulos, Evangelos
Romanidis, Konstantinos
Oikonomou, Panagoula
Steiropoulos, Paschalis
Trakada, Georgia
Vagionas, Anastasios
Ioannidis, Aris
Katsios, Iason Nikolaos
Goganau, Alexandru Marian
Zarogoulidis, Pavlos
Kosmidis, Christoforos
Gender Differences in Obstructive Sleep Apnea: The Value of Sleep Questionnaires with a Separate Analysis of Cardiovascular Patients
title Gender Differences in Obstructive Sleep Apnea: The Value of Sleep Questionnaires with a Separate Analysis of Cardiovascular Patients
title_full Gender Differences in Obstructive Sleep Apnea: The Value of Sleep Questionnaires with a Separate Analysis of Cardiovascular Patients
title_fullStr Gender Differences in Obstructive Sleep Apnea: The Value of Sleep Questionnaires with a Separate Analysis of Cardiovascular Patients
title_full_unstemmed Gender Differences in Obstructive Sleep Apnea: The Value of Sleep Questionnaires with a Separate Analysis of Cardiovascular Patients
title_short Gender Differences in Obstructive Sleep Apnea: The Value of Sleep Questionnaires with a Separate Analysis of Cardiovascular Patients
title_sort gender differences in obstructive sleep apnea: the value of sleep questionnaires with a separate analysis of cardiovascular patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019723/
https://www.ncbi.nlm.nih.gov/pubmed/31947711
http://dx.doi.org/10.3390/jcm9010130
work_keys_str_mv AT patakaathanasia genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT kotoulasseraphim genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT kalamarasgeorge genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT schizasofia genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT sapalidiskonstantinos genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT giannakidisdimitirios genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT michalopoulosnikolaos genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT koulourischarilaos genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT aidonizoi genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT amanitiaikaterini genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT bouloukakiizoldi genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT chatzopoulosevangelos genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT romanidiskonstantinos genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT oikonomoupanagoula genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT steiropoulospaschalis genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT trakadageorgia genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT vagionasanastasios genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT ioannidisaris genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT katsiosiasonnikolaos genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT goganaualexandrumarian genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT zarogoulidispavlos genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients
AT kosmidischristoforos genderdifferencesinobstructivesleepapneathevalueofsleepquestionnaireswithaseparateanalysisofcardiovascularpatients