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Feline Infectious Peritonitis Virus Nsp5 Inhibits Type I Interferon Production by Cleaving NEMO at Multiple Sites

Feline infectious peritonitis (FIP), caused by virulent feline coronavirus, is the leading infectious cause of death in cats. The type I interferon (type I IFN)-mediated immune responses provide host protection from infectious diseases. Several coronaviruses have been reported to evolve diverse stra...

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Detalles Bibliográficos
Autores principales: Chen, Si, Tian, Jin, Li, Zhijie, Kang, Hongtao, Zhang, Jikai, Huang, Jiapei, Yin, Hang, Hu, Xiaoliang, Qu, Liandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019732/
https://www.ncbi.nlm.nih.gov/pubmed/31905881
http://dx.doi.org/10.3390/v12010043