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Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover

The 2010 Alcohol Hangover Research Group consensus paper defined a cutoff blood alcohol concentration (BAC) of 0.11% as a toxicological threshold indicating that sufficient alcohol had been consumed to develop a hangover. The cutoff was based on previous research and applied mostly in studies compri...

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Autores principales: Verster, Joris C., Kruisselbrink, L. Darren, Slot, Karin A., Anogeianaki, Aikaterini, Adams, Sally, Alford, Chris, Arnoldy, Lizanne, Ayre, Elisabeth, Balikji, Stephanie, Benson, Sarah, Bruce, Gillian, Devenney, Lydia E., Frone, Michael R., Gunn, Craig, Heffernan, Thomas, Hensel, Kai O., Hogewoning, Anna, Johnson, Sean J., van Lawick van Pabst, Albertine E., van de Loo, Aurora J.A.E., Mackus, Marlou, Merlo, Agnese, Murphy, René J.L., Owen, Lauren, Palmer, Emily O.C., van Rossum, Charmaine J.I., Scholey, Andrew, Terpstra, Chantal, Vatsalya, Vatsalya, Vermeulen, Sterre A., van Wijk, Michelle, Stock, Ann-Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019760/
https://www.ncbi.nlm.nih.gov/pubmed/31936502
http://dx.doi.org/10.3390/jcm9010179
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author Verster, Joris C.
Kruisselbrink, L. Darren
Slot, Karin A.
Anogeianaki, Aikaterini
Adams, Sally
Alford, Chris
Arnoldy, Lizanne
Ayre, Elisabeth
Balikji, Stephanie
Benson, Sarah
Bruce, Gillian
Devenney, Lydia E.
Frone, Michael R.
Gunn, Craig
Heffernan, Thomas
Hensel, Kai O.
Hogewoning, Anna
Johnson, Sean J.
van Lawick van Pabst, Albertine E.
van de Loo, Aurora J.A.E.
Mackus, Marlou
Merlo, Agnese
Murphy, René J.L.
Owen, Lauren
Palmer, Emily O.C.
van Rossum, Charmaine J.I.
Scholey, Andrew
Terpstra, Chantal
Vatsalya, Vatsalya
Vermeulen, Sterre A.
van Wijk, Michelle
Stock, Ann-Kathrin
author_facet Verster, Joris C.
Kruisselbrink, L. Darren
Slot, Karin A.
Anogeianaki, Aikaterini
Adams, Sally
Alford, Chris
Arnoldy, Lizanne
Ayre, Elisabeth
Balikji, Stephanie
Benson, Sarah
Bruce, Gillian
Devenney, Lydia E.
Frone, Michael R.
Gunn, Craig
Heffernan, Thomas
Hensel, Kai O.
Hogewoning, Anna
Johnson, Sean J.
van Lawick van Pabst, Albertine E.
van de Loo, Aurora J.A.E.
Mackus, Marlou
Merlo, Agnese
Murphy, René J.L.
Owen, Lauren
Palmer, Emily O.C.
van Rossum, Charmaine J.I.
Scholey, Andrew
Terpstra, Chantal
Vatsalya, Vatsalya
Vermeulen, Sterre A.
van Wijk, Michelle
Stock, Ann-Kathrin
author_sort Verster, Joris C.
collection PubMed
description The 2010 Alcohol Hangover Research Group consensus paper defined a cutoff blood alcohol concentration (BAC) of 0.11% as a toxicological threshold indicating that sufficient alcohol had been consumed to develop a hangover. The cutoff was based on previous research and applied mostly in studies comprising student samples. Previously, we showed that sensitivity to hangovers depends on (estimated) BAC during acute intoxication, with a greater percentage of drinkers reporting hangovers at higher BAC levels. However, a substantial number of participants also reported hangovers at comparatively lower BAC levels. This calls the suitability of the 0.11% threshold into question. Recent research has shown that subjective intoxication, i.e., the level of severity of reported drunkenness, and not BAC, is the most important determinant of hangover severity. Non-student samples often have a much lower alcohol intake compared to student samples, and overall BACs often remain below 0.11%. Despite these lower BACs, many non-student participants report having a hangover, especially when their subjective intoxication levels are high. This may be the case when alcohol consumption on the drinking occasion that results in a hangover significantly exceeds their “normal” drinking level, irrespective of whether they meet the 0.11% threshold in any of these conditions. Whereas consumers may have relative tolerance to the adverse effects at their “regular” drinking level, considerably higher alcohol intake—irrespective of the absolute amount—may consequentially result in a next-day hangover. Taken together, these findings suggest that the 0.11% threshold value as a criterion for having a hangover should be abandoned.
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spelling pubmed-70197602020-03-09 Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover Verster, Joris C. Kruisselbrink, L. Darren Slot, Karin A. Anogeianaki, Aikaterini Adams, Sally Alford, Chris Arnoldy, Lizanne Ayre, Elisabeth Balikji, Stephanie Benson, Sarah Bruce, Gillian Devenney, Lydia E. Frone, Michael R. Gunn, Craig Heffernan, Thomas Hensel, Kai O. Hogewoning, Anna Johnson, Sean J. van Lawick van Pabst, Albertine E. van de Loo, Aurora J.A.E. Mackus, Marlou Merlo, Agnese Murphy, René J.L. Owen, Lauren Palmer, Emily O.C. van Rossum, Charmaine J.I. Scholey, Andrew Terpstra, Chantal Vatsalya, Vatsalya Vermeulen, Sterre A. van Wijk, Michelle Stock, Ann-Kathrin J Clin Med Communication The 2010 Alcohol Hangover Research Group consensus paper defined a cutoff blood alcohol concentration (BAC) of 0.11% as a toxicological threshold indicating that sufficient alcohol had been consumed to develop a hangover. The cutoff was based on previous research and applied mostly in studies comprising student samples. Previously, we showed that sensitivity to hangovers depends on (estimated) BAC during acute intoxication, with a greater percentage of drinkers reporting hangovers at higher BAC levels. However, a substantial number of participants also reported hangovers at comparatively lower BAC levels. This calls the suitability of the 0.11% threshold into question. Recent research has shown that subjective intoxication, i.e., the level of severity of reported drunkenness, and not BAC, is the most important determinant of hangover severity. Non-student samples often have a much lower alcohol intake compared to student samples, and overall BACs often remain below 0.11%. Despite these lower BACs, many non-student participants report having a hangover, especially when their subjective intoxication levels are high. This may be the case when alcohol consumption on the drinking occasion that results in a hangover significantly exceeds their “normal” drinking level, irrespective of whether they meet the 0.11% threshold in any of these conditions. Whereas consumers may have relative tolerance to the adverse effects at their “regular” drinking level, considerably higher alcohol intake—irrespective of the absolute amount—may consequentially result in a next-day hangover. Taken together, these findings suggest that the 0.11% threshold value as a criterion for having a hangover should be abandoned. MDPI 2020-01-09 /pmc/articles/PMC7019760/ /pubmed/31936502 http://dx.doi.org/10.3390/jcm9010179 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Verster, Joris C.
Kruisselbrink, L. Darren
Slot, Karin A.
Anogeianaki, Aikaterini
Adams, Sally
Alford, Chris
Arnoldy, Lizanne
Ayre, Elisabeth
Balikji, Stephanie
Benson, Sarah
Bruce, Gillian
Devenney, Lydia E.
Frone, Michael R.
Gunn, Craig
Heffernan, Thomas
Hensel, Kai O.
Hogewoning, Anna
Johnson, Sean J.
van Lawick van Pabst, Albertine E.
van de Loo, Aurora J.A.E.
Mackus, Marlou
Merlo, Agnese
Murphy, René J.L.
Owen, Lauren
Palmer, Emily O.C.
van Rossum, Charmaine J.I.
Scholey, Andrew
Terpstra, Chantal
Vatsalya, Vatsalya
Vermeulen, Sterre A.
van Wijk, Michelle
Stock, Ann-Kathrin
Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover
title Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover
title_full Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover
title_fullStr Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover
title_full_unstemmed Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover
title_short Sensitivity to Experiencing Alcohol Hangovers: Reconsideration of the 0.11% Blood Alcohol Concentration (BAC) Threshold for Having a Hangover
title_sort sensitivity to experiencing alcohol hangovers: reconsideration of the 0.11% blood alcohol concentration (bac) threshold for having a hangover
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019760/
https://www.ncbi.nlm.nih.gov/pubmed/31936502
http://dx.doi.org/10.3390/jcm9010179
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